Everything, when administered orally, is absorbed from the gastrointestinal tract into the portal venous circulation and pass through the liver (first pass metabolism) where the process of metabolism or breakdown begins. Suppositories, like intravenous (IV), intramuscular (IM), and transdermal methods of administration, bypass this “first pass” effect and are absorbed into the rectal veins without encountering liver metabolism. Fortunately, the rectum is filled with blood vessels that offer direct access into the body’s bloodstream. This allows for rapid access to systemic circulation.
When nutrients are put into our special suppository base they are protected and delivered through Slow Release Technology along with the support of the probiotics APO-808. All Glutagenic’s™’s proprietary suppository base is formulated with ingredients that promote the movement of the active nutrients from the base to the rectum. This technology facilitates solubility, and allows a compound that is usually insoluble in water (hydrophobic) to dissolve, and thus be absorbed. This is crucial for poorly absorbed compounds.
ABC’s suppositories are easy to insert, non-irritating, rapid-melting, fully absorbed in 5-10 minutes, and you’ll not know its in there after insertion.